Blood management in older adults questioned

Published:

Geoff Simon in lab

USC-led research exploring blood management in older patients with anaemia and blood loss has raised questions around the current recommended medical care approach.

Lead author and USC academic Geoff Simon said current worldwide adult medical guidelines for blood transfusions are based mainly on data from people under the age of 65.

“Blood management in older adults who are sick is not something that has been widely studied and therefore a lot of the guidance for these patients uses a one-size-fits-all type approach,” Mr Simon said.

“Often this means that the restrictive, or lower, haemoglobin thresholds that guide blood use for people under 65 don’t work as well as they could for older patients,” he said.

“It is great to see that transfusion rates are going down in general as per blood management guidelines, but our research suggests that we could be managing things differently for better outcomes in older adults.”

Geoff Simon said anaemia is associated with worse outcomes in older adults, but the reasons are not well understood. The USC research has focussed on changes in oxygen delivery to the body with older age due to factors such as falling cardiac performance.

“Our research analysed the use of blood in older patients based on some international trials. We found that the older patients who were managed with haemoglobin levels around 100 g per litre had a lower mortality rate and had fewer cardiac complications than those managed around 70 or 80 g per litre,” Mr Simon said.

“We then reviewed further evidence to explore the biological reasons behind differences in transfusion trial outcomes related to haemoglobin thresholds in different age groups,” he said.

“Based on those findings the research team predicted that older adults require a haemoglobin of 100g per litre to achieve the same oxygen delivery potential as a younger patient with haemoglobin of 70g per litre.

“We believe this indicates the need for patient blood management guidance to be much more specific to older adults, and distinct from younger adults.

“It reinforces the need to conserve the patients’ blood and to investigate and treat the causes of anaemia in older adults, so they are better able to cope with physical demands.

 “This could offer much better outcomes to older patients with anaemia both in a hospital setting but also in community settings to better their quality of life.”

Impacts of Aging on Anaemia Tolerance, Transfusion Thresholds, and Patient Blood Management was recently published in international journal Transfusion Medicine Review and is listed at the top of the review’s articles with the most social media attention from 2017-2019.
 

 
Community Health & Wellness Science & Research University & TAFE
Social:   

University Of The Sunshine Coast : View Full Profile
90 Sippy Downs Drive, Sippy Downs
07 5430 1234
University Of The Sunshine Coast
Showing 10+ recent articles for this business
USC to host Lightning’s Community Thank You event 15 September 2019 | USC is hosting the event to give fans the chance to meet players and coaching staff, collect signatures, and to say farewell to the club’s foundation coach Noeline Taurua. More information...
A meeting of cultures for print symposium 11 September 2019 | USC’s Art Gallery will soon host a two-day public forum featuring a Japanese print art expert to coincide with the opening of a stunning exhibition of Japanese and Australian print art at Caloundra Regional... More information...
USC Journalism graduate wins statewide award 10 September 2019 | Drew Beveridge is no doubt flying high after she was named Queensland’s most outstanding final-year journalism student. More information...
USC backs Lightning with ‘wear yellow to work’ day 10 September 2019 | USC staff will be sporting the colour yellow tomorrow (Wednesday 11 September) as a bright show of support for Sunshine Coast Lightning ahead of the Suncorp Super Netball grand final on Sunday 15 September. More information...
Today is World Suicide Prevention Day 10 September 2019 | We have received overwhelming response from the community in support of our World Suicide Prevention Day mission: to train 100 people as suicide-alert community gatekeepers. We see gatekeepers as people whose... More information...
Study finds value for money trumps online ratings 09 September 2019 | Online reviews have revolutionised the way travellers select hotels, but a USC researcher has found when it comes to swaying consumers, ratings cannot beat old fashioned price and location.  More information...
Peony scientist breaks new ground for cut flowers 09 September 2019 | One of the world’s most popular flowers – the peony – can now be grown in hot climates, following a discovery that could disrupt the multi-billion dollar global cut flower industry. More information...
Journalism students in running for state award 06 September 2019 | Two USC journalism students have been named as finalists in the Queensland Clarion Awards being held in Brisbane tomorrow night (Saturday 7 September). More information...
USC nappy project changing lives in Vanuatu 05 September 2019 | A USC Occupational Therapy student from Burpengary is determined to make a difference to the lives of disadvantaged mothers and babies in Vanuatu – one reusable nappy at a time.  More information...
Year 11 student to discuss benefits of Headstart 05 September 2019 | Studying a human anatomy subject at university while in Year 11 is part of Chancellor State College student Petra Nunn’s plan to eventually become a doctor. More information...


comments powered by Disqus

All articles submitted by third parties or written by My Sunshine Coast come under our Disclaimer / Terms of Service