Commissioner Ian Stewart said research had shown that a high police presence on major road networks during peak holiday periods provided community reassurance and also served as a deterrent to those engaging in high-risk behaviour.
"Officers will be out in force conducting roadside testing for drugs and alcohol, as well as covert and overt speed enforcement in high-risk zones," Commissioner Stewart said.
"From today until April 26, anyone travelling on the state's highways can expect to encounter police."
The Easter Road Safety campaign will target the Fatal Five – speeding, drink/drug, fatigue, seat belt use and driver distraction/inattention.
Minister Ryan said the Queensland Government and QPS were committed to reducing the road toll.
"Each Easter period the government stands alongside the QPS to urge all Queenslanders to drive safely.
"We do this because we want there to be zero fatalities," Minister Ryan said.
The Member for Aspley urged all road users to be extra careful on the roads this year.
"I want everyone to have a great holiday with their families but I also want everyone to make sure this holiday period is a safe one for all Queenslanders," Mr Mellish said.